Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065314 | 0.87 | NPC1 (0.43) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL547800 | 0.87 | NPC1 (0.43) | NPC1RAB9APOLBKDM4ELMNA | |
| Ammonia Solution, Strong SCHEMBL6829752 | 0.86 | NPC1 (0.42) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL7514663 | 0.86 | NPC1 (0.45) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL2065312 | 0.86 | NPC1 (0.42) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL2065313 | 0.85 | POLB (0.43) | NPC1RAB9APOLBKDM4ELMNA | |
| Sulfuric Acid SCHEMBL27655805 | 0.82 | NPC1 (0.42) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL7511427 | 0.81 | NPC1 (0.38) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL8777471 | 0.80 | NPC1 (0.49) | NPC1RAB9APOLBKDM4ELMNA | |
| SCHEMBL3381678 | 0.80 | NPC1 (0.59) | NPC1RAB9APOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272490-B1 | Stabilization of body-care and household products against degradation by UV radiation using merocyanine derivatives | BASF SE (DE) | 2019-10-16 | — | — | EP | disclosed |