Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065314 | 0.89 | NPC1 (0.43) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL547800 | 0.89 | NPC1 (0.43) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2065312 | 0.88 | NPC1 (0.42) | NPC1RAB9APOLBLMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL6829752 | 0.88 | NPC1 (0.42) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2065313 | 0.87 | POLB (0.43) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL21486148 | 0.86 | NPC1 (0.41) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL7511427 | 0.83 | NPC1 (0.38) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL11618064 | 0.82 | NPC1 (0.53) | NPC1RAB9APOLBLMNAKDM4E | |
| Sulfuric Acid SCHEMBL27655805 | 0.81 | NPC1 (0.42) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL3381678 | 0.81 | NPC1 (0.59) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179924-B2 | Use of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| US-7179924-B2 | Use of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-02-20 | — | — | US | disclosed |
| US-6495125-B2 | MAY BE USED IN HAIR CARE, TEXTILE CARE, COSMETICS, ORAL CARE FORMULATIONS, SKIN, NAIL, LAUNDRY, ACNE CARE FORMULATIONS | THE PROCTER & GAMBLE COMPANY | 2002-12-17 | — | — | US | disclosed |
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | PROCTER & GAMBLE COMPANY, THE | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020012639-A1 | May be used in hair care, textile care, cosmetics, oral care formulations, skin, nail, laundry, acne care formulations | SCLY, TST, SRR | NPC1 3256/4885RAB9A 2874/4885POLB 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.