⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150361 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL8987948 | 0.80 | MAPT (0.42) | — | |
| SCHEMBL11862202 | 0.77 | — | — | |
| SCHEMBL18570976 | 0.77 | — | — | |
| SCHEMBL18571304 | 0.76 | — | — | |
| SCHEMBL25594578 | 0.76 | — | — | |
| SCHEMBL18571207 | 0.74 | — | — | |
| SCHEMBL18570933 | 0.74 | — | — | |
| SCHEMBL1469710 | 0.71 | — | — | |
| SCHEMBL12475563 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200114-A1 | METHODS FOR PREPARING SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDE COMPOUNDS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-10-17 | — | — | WO | disclosed |