SCHEMBL8987948

SCHEMBL8987948

CC=CC(F)CCCCCC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.38
DNM1 Q05193 2/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH4 P08319 1/20 0.36
ADH7 P40394 1/20 0.36
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
CA2 P00918 1/20 0.36
OPRM1 P35372 1/20 0.36
SMPD1 P17405 3/20 0.35
TRPA1 O75762 1/20 0.35
DDAH1 O94760 1/20 0.35
GAPDH P04406 1/20 0.35
SLC22A1 O15245 1/20 0.35
LSS P48449 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8047265 0.85 MAPT (0.43) MAPTLMNADNM1ADH1BADH1C
SCHEMBL28052568 0.84 LMNA (0.42) MAPTLMNADNM1ADH1BADH1C
SCHEMBL2319980 0.81 MAPT (0.45) MAPTLMNADNM1ADH1BADH1C
SCHEMBL21486310 0.80
SCHEMBL7206547 0.78 MEN1 (0.47) MAPTLMNATHRB
SCHEMBL9755655 0.76 MAPT (0.50) MAPTLMNADNM1ADH1BADH1C
SCHEMBL1667132 0.76 MAPT (0.50) MAPTLMNADNM1ADH1BADH1C
SCHEMBL9755658 0.76 MAPT (0.50) MAPTLMNADNM1ADH1BADH1C
SCHEMBL11858917 0.76 MAPT (0.45) MAPTLMNADNM1ADH1BADH1C
SCHEMBL31243205 0.76 MAPT (0.50) MAPTLMNADNM1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5585395-A INSECTICIDES, MITICIDES, FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1996-12-17 US disclosed