Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31625491 | 0.62 | PDE10A (0.52) | — | |
| SCHEMBL31625035 | 0.58 | CHEK1 (0.31) | CHEK1GRK5CSNK1A1LIMK1TYRO3 | |
| SCHEMBL2148531 | 0.55 | — | — | |
| SCHEMBL20781 | 0.53 | — | — | |
| SCHEMBL1332087 | 0.53 | — | — | |
| SCHEMBL31064887 | 0.50 | ALDH1A1 (0.89) | ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL11176077 | 0.50 | ALDH1A1 (0.89) | ALDH1A1ALOX15TSHR | |
| SCHEMBL31212831 | 0.50 | ALDH1A1 (0.89) | ALDH1A1ALOX15TSHR | |
| SCHEMBL1163861 | 0.50 | ALDH1A1 (0.89) | ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL28513754 | 0.50 | ALDH1A1 (0.89) | ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |