Benzene

Benzene

SCHEMBL2148681

O=S(=O)(O)NCl.[NaH].c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ACP1 P24666 2/20 0.34
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL630832 0.97 ACP1 (0.33) TSHRSMN1; SMN2ACP1
Benzene SCHEMBL3130121 0.97 TSHR (0.36) TSHRSMN1; SMN2ACP1CA5ACA5B
SCHEMBL10645073 0.89
SCHEMBL278347 0.86
SCHEMBL28227822 0.82
Water SCHEMBL9558051 0.82
SCHEMBL28227840 0.82
SCHEMBL31707826 0.82
SCHEMBL28227036 0.82
SCHEMBL28227824 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2865743-B1 Improvements in dispensing devices RECKITT BENCKISER LLC (US) 2024-03-27 EP disclosed
US-8776277-B2 Lavatory dispensing device RECKITT BENCKISER LLC (US) 2014-07-15 US disclosed
US-8719971-B2 Lavatory dispensing devices RECKITT BENCKISER LLC (US) 2014-05-13 US disclosed
US-20110219525-A1 Lavatory Dispensing Devices RECKITT BENCKISER LLC (US) 2011-09-15 US disclosed
US-20110173742-A1 Lavatory Dispensing Device RECKITT BENCKISER LLC (US) 2011-07-21 US disclosed
EP-2342391-A1 LAVATORY DISPENSING DEVICES Reckitt Benckiser LLC (US) 2011-07-13 EP disclosed
US-20100146687-A1 Lavatory Dispensing Devices RECKITT BENCKISER INC. (US) 2010-06-17 US disclosed
WO-2010037997-A1 LAVATORY DISPENSING DEVICES RECKITT BENCKISER INC. (US) 2010-04-08 WO disclosed
WO-2010007337-A1 IMPROVEMENTS IN LAVATORY DISPENSING DEVICES RECKITT BENCKISER INC. (US) 2010-01-21 WO disclosed
WO-2007107769-A1 IMPROVEMENTS IN LAVATORY DISPENSING DEVICES RECKITT BENCKISER INC. (US) 2007-09-27 WO disclosed
US-3943243-A SODIUM BISULFATE, P-DICHLORO-BENZENE OR NAPHTHALENE E. I. DU PONT DE NEMOURS AND CO. (US) 1976-03-09 US disclosed