Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148535 | 0.90 | MTOR (0.66) | MTOR | |
| SCHEMBL18156570 | 0.84 | MTOR (0.55) | MTOR | |
| SCHEMBL18142959 | 0.83 | MTOR (0.56) | MTOR | |
| SCHEMBL13718899 | 0.81 | MTOR (0.56) | MTOR | |
| SCHEMBL18142971 | 0.81 | MTOR (0.56) | MTOR | |
| SCHEMBL18142952 | 0.81 | MTOR (0.55) | MTOR | |
| SCHEMBL18142942 | 0.81 | ALDH1A1 (0.55) | MTOR | |
| SCHEMBL18142958 | 0.80 | MTOR (0.75) | MTOR | |
| SCHEMBL18142956 | 0.79 | MTOR (0.73) | MTOR | |
| SCHEMBL2148703 | 0.79 | MTOR (0.85) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519102-A2 | NOVEL PYRIMIDINE COMPOUNDS AS mTOR AND PI3K INHIBITORS | Development Center For Biotechnology (TW) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080568-A2 | NOVEL PYRIMIDINE COMPOUNDS AS MTOR AND P13K INHIBITORS | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2011-07-07 | — | — | WO | disclosed |