Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146485 | 0.91 | PDE1A (0.31) | PDE1APDE1BPDE1C | |
| SCHEMBL14798762 | 0.86 | S1PR1 (0.44) | — | |
| SCHEMBL2146715 | 0.82 | S1PR1 (0.40) | PDE1APDE1BPDE1C | |
| SCHEMBL2146687 | 0.80 | PPARA (0.34) | — | |
| SCHEMBL2146203 | 0.79 | PTGS2 (0.31) | — | |
| SCHEMBL2146481 | 0.79 | S1PR1 (0.33) | — | |
| SCHEMBL2146707 | 0.79 | S1PR1 (0.38) | PDE1APDE1BPDE1C | |
| SCHEMBL2146681 | 0.79 | NPSR1 (0.34) | — | |
| SCHEMBL2146623 | 0.78 | S1PR1 (0.39) | — | |
| SCHEMBL2146320 | 0.78 | S1PR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086077-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | claimed |