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SCHEMBL2149231

SCHEMBL2149231

CCCCOC1(c2ccccc2C)CN(C(c2ccc(OC)cc2OC(=O)C(F)(F)F)C(N)C=O)C1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MC1R Q01726 7/20 0.40
▸ MC4R P32245 7/20 0.40
▸ APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1311385 0.80 MC1R (0.49) MC1RMC4RAPP
Hydrochloric Acid SCHEMBL2148837 0.79 MC1R (0.45) MC1RMC4RAPP
SCHEMBL2161645 0.74 MC1R (0.43) MC1RMC4RAPP
SCHEMBL1310202 0.74 MC1R (0.47) MC1RMC4R
SCHEMBL1310191 0.72 MC1R (0.49) MC1RMC4R
SCHEMBL1309979 0.72 MC1R (0.50) MC1RMC4RAPP
SCHEMBL1309669 0.72 MC1R (0.40) MC1RMC4RAPP
SCHEMBL2148734 0.71 MC1R (0.37) MC1RMC4R
Trifluoroacetic Acid SCHEMBL1310217 0.70 MC1R (0.57) MC1RMC4R
Trifluoroacetic Acid SCHEMBL1311384 0.70 MC1R (0.58) MC1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2342194-A1 OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS Galderma Research & Development (FR) 2011-07-13 — — EP disclosed
WO-2010052253-A1 OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-05-14 — — WO disclosed