Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 7/20 | 0.37 |
| ▸ | MC4R | P32245 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1310165 | 0.76 | MC1R (0.49) | MC1RMC4RDPP4DPP7DPP8 | |
| SCHEMBL1310335 | 0.75 | PDK2 (0.34) | MC1RMC4RFAAHDPP8 | |
| SCHEMBL1309979 | 0.74 | MC1R (0.50) | MC1RMC4RDPP4DPP7CACNA1A | |
| Hydrochloric Acid SCHEMBL2148837 | 0.73 | MC1R (0.45) | MC1RMC4RFAAHALDH1A1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL1309977 | 0.71 | MC1R (0.56) | MC1RMC4RDPP4DPP7DPP8 | |
| SCHEMBL27827356 | 0.70 | MC1R (0.44) | MC1RMC4RFAAHKMT2AMEN1 | |
| SCHEMBL2148981 | 0.69 | MC1R (0.40) | MC1RMC4RKMT2AMEN1ALDH1A1 | |
| SCHEMBL2161645 | 0.68 | MC1R (0.43) | MC1RMC4R | |
| SCHEMBL16445371 | 0.68 | MC1R (0.62) | MC1RMC4RKMT2A | |
| SCHEMBL1312669 | 0.67 | GPR119 (0.39) | MC1RMC4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |