Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27578446 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL28983783 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL28545117 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL594635 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL28730749 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL584403 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL28537300 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL29019024 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL9482055 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL26105712 | 1.00 | DNM1 (0.46) | DNM1TSHRALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201221-A1 | MODIFIED STARCH AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 瑞辰星生物技术（广州）有限公司 | 2019-10-24 | — | — | WO | disclosed |