Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.34 |
| ▸ | RXRB | P28702 | 7/20 | 0.33 |
| ▸ | RXRG | P48443 | 4/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798637 | 0.88 | S1PR1 (0.46) | RXRARXRBRXRGMRGPRX4S1PR1 | |
| SCHEMBL2148943 | 0.85 | SMN1; SMN2 (0.34) | S1PR1 | |
| SCHEMBL2146681 | 0.84 | NPSR1 (0.34) | S1PR1 | |
| SCHEMBL2146481 | 0.84 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL2146715 | 0.82 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL2146687 | 0.80 | PPARA (0.34) | S1PR1SCN9A | |
| SCHEMBL2146623 | 0.80 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL2146320 | 0.80 | S1PR1 (0.50) | S1PR1 | |
| SCHEMBL2146207 | 0.80 | S1PR1 (0.39) | S1PR1 | |
| SCHEMBL2146707 | 0.79 | S1PR1 (0.38) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523958-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086077-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |