Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 19/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.51 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494623 | 1.00 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL30106777 | 1.00 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494679 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL31657846 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494675 | 0.84 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494695 | 0.83 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL30106798 | 0.83 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494697 | 0.83 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494625 | 0.83 | FPR2 (0.71) | FPR2MTHFD1MTHFD2 | |
| Hydrochloric Acid SCHEMBL21494810 | 0.83 | FPR2 (0.98) | FPR2MTHFD1MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | Thomas Helledays stiftelse för medicinsk forskning (SE) | 2021-02-24 | — | — | EP | claimed |
| WO-2019201991-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2019-10-24 | — | — | WO | claimed |
| CN-112218858-B | 2, 6-Diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-06-18 | — | — | CN | disclosed |