Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16286464 | 0.75 | SRC (0.34) | HDAC4SRCCTSKAKR1C1KMT2A | |
| SCHEMBL1493256 | 0.75 | KMT2A (0.42) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL1408833 | 0.75 | HDAC4 (0.44) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL28854800 | 0.73 | AKR1B1 (0.47) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8994348 | 0.69 | SRC (0.46) | SRCLMNACES1SLC6A2 | |
| SCHEMBL28444682 | 0.69 | OPRL1 (0.56) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL29262368 | 0.68 | HDAC4 (0.43) | HDAC4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL2767076 | 0.68 | CES1 (0.41) | HDAC4SRCCTSKAKR1C1KMT2A | |
| SCHEMBL323272 | 0.67 | AKR1C3 (0.47) | HDAC4AKR1C1 | |
| SCHEMBL17353520 | 0.67 | OPRL1 (0.41) | HDAC4OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202796-A1 | POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR | 信越化学工業株式会社 | 2019-10-24 | — | — | WO | disclosed |