SCHEMBL8994348

SCHEMBL8994348

CC(O)(Cc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
CES1 P23141 2/20 0.45
SLC6A2 P23975 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
FDPS P14324 1/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 2/20 0.42
CYP2D6 P10635 1/20 0.42
TRPA1 O75762 1/20 0.42
MMP8 P22894 3/20 0.41
RECQL P46063 1/20 0.41
PTPN1 P18031 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10944429 0.93 ALDH1A1 (0.47) ALDH1A1MMP8PPARGPPARARAB9A
SCHEMBL11084523 0.90 NPC1 (0.47) SRCSMN1; SMN2CES1LMNARECQL
SCHEMBL2950246 0.85 LMNA (0.40) SRCSMN1; SMN2CES1CYP2C9CYP2C19
SCHEMBL1618561 0.85 RAB9A (0.50) SMN1; SMN2HIF1ACYP2C9ALDH1A1CYP2D6
SCHEMBL8459206 0.82 MMP8 (0.50) SRCSMN1; SMN2HIF1ACES1SLC6A2
SCHEMBL7104524 0.82 SLC6A2 (0.52) SRCSMN1; SMN2HIF1ACES1SLC6A2
SCHEMBL3361395 0.82 SMN1; SMN2 (0.55) SMN1; SMN2HIF1ACES1SLC6A2TAAR1
SCHEMBL11292363 0.82 CES1 (0.50) SRCSMN1; SMN2HIF1ACES1CYP2C19
SCHEMBL4359977 0.82 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACES1SLC6A2TAAR1
SCHEMBL1275761 0.82 SMN1; SMN2 (0.55) SMN1; SMN2HIF1ACES1SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111240073-B Display panel, manufacturing method thereof and display device 京东方科技集团股份有限公司 2023-01-17 CN disclosed
EP-0386650-B1 Aqueous disperse systems of photoinitiators and their use LAMBERTI SPA (IT) 1996-08-21 EP disclosed
US-5225104-A Polymer dispersed liquid crystal films having improved optical performance GENERAL MOTORS CORPORATION (US) 1993-07-06 US disclosed
US-5168087-A Mixture with surfactant FRATELLI LAMBERTI S.P.A. (IT) 1992-12-01 US disclosed
EP-0003002-B1 USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES CIBA-GEIGY AG (CH) 1984-06-13 EP disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed