Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL288042 | 0.89 | SLC22A1 (0.46) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL1577203 | 0.88 | SLC22A1 (0.55) | SLC22A1SLC22A2LMNAESR1ADORA3 | |
| Tetrabuthylammonium SCHEMBL1577204 | 0.88 | SLC22A1 (0.55) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL21855087 | 0.88 | SLC22A1 (0.55) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL769197 | 0.88 | SLC22A1 (0.55) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL30049697 | 0.87 | SLC22A1 (0.44) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL22034330 | 0.87 | SLC22A1 (0.44) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL1332663 | 0.87 | SLC22A1 (0.38) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL21855085 | 0.86 | SLC22A1 (0.52) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 | |
| Tetrabuthylammonium SCHEMBL21545821 | 0.86 | SLC22A1 (0.52) | SLC22A1LPAR3LPAR1LPAR2SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756852-A | Preparation method of cocarboxylase tetrahydrate | 燃点(南京)生物医药科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117756852-A | Preparation method of cocarboxylase tetrahydrate | 燃点(南京)生物医药科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-116986584-B | Preparation method of nitrogen, phosphorus and iron doped carbon material and application of nitrogen, phosphorus and iron doped carbon material in rubber | 河北省科学院能源研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-116986584-A | Preparation method of nitrogen, phosphorus and iron doped carbon material and application of nitrogen, phosphorus and iron doped carbon material in rubber | 河北省科学院能源研究所 | 2023-11-03 | — | — | CN | disclosed |
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MERCK SHARP & DOHME LLC (US) | 2023-01-03 | — | — | US | disclosed |
| EP-3781687-A1 | NOVEL SUBSTITUTED RIG-I AGONISTS: COMPOSITIONS AND METHODS THEREOF | Merck Sharp&Dohme Corp. (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204179-A1 | NOVEL SUBSTITUTED RIG-I AGONISTS: COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542505-B1 | Substituted RIG-I agonists: compositions and methods thereof | MAVS, TLR3, DDX18 | SLC22A1 4090/4885LPAR3 606/4885LPAR1 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.