Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496444 | 1.00 | CRBN (0.62) | CRBNDDB1 | |
| SCHEMBL21496453 | 0.81 | CRBN (0.68) | CRBNDDB1 | |
| SCHEMBL21496486 | 0.80 | CRBN (0.72) | CRBNDDB1 | |
| SCHEMBL21496461 | 0.77 | CRBN (0.82) | CRBNDDB1 | |
| SCHEMBL22931831 | 0.77 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL21496431 | 0.75 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL29346902 | 0.75 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL21496491 | 0.74 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL29346922 | 0.73 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL22932165 | 0.73 | CRBN (0.65) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781156-A1 | SPIROCYCLIC COMPOUNDS | C4 Therapeutics, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204354-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |