SCHEMBL29346902

SCHEMBL29346902

CC(=O)N1CCN(Cc2ccc(N3CCC4(CCCC(=O)NC4=O)C3)nc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 12/20 0.55
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
DDB1 Q16531 1/20 0.46
AOC3 Q16853 1/20 0.41
HRH3 Q9Y5N1 2/20 0.41
ICAM1 P05362 1/20 0.40
LTA4H P09960 1/20 0.38
WNT3A P56704 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29346922 0.89 CRBN (0.51) CRBNDDB1
SCHEMBL31068608 0.88 CRBN (0.59) CRBNDDB1WNT3A
SCHEMBL31730049 0.75 CRBN (0.57) CRBNDDB1
SCHEMBL29346919 0.75 CRBN (0.62) CRBNDDB1
SCHEMBL21496444 0.75 CRBN (0.62) CRBNDDB1
SCHEMBL21496445 0.75 CRBN (0.62) CRBNDDB1
SCHEMBL29346912 0.74 CRBN (0.55) CRBNDDB1
SCHEMBL29346926 0.74 CRBN (0.58) CRBNDDB1
SCHEMBL29345989 0.73 CRBN (0.89) CRBNDDB1
SCHEMBL29346920 0.73 CRBN (0.69) CRBNMEN1KMT2ADDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL CRBN 1/4885MEN1 859/4885KMT2A 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.