SCHEMBL21496516

SCHEMBL21496516

CC(=O)NC(C)CN(C(C)=O)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.38
MTNR1B P49286 8/20 0.38
ALDH1A1 P00352 1/20 0.38
ACACB O00763 6/20 0.37
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
PTGS2 P35354 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ACACA Q13085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21513624 0.80 ACACB (0.37) MTNR1AMTNR1BALDH1A1ACACBKDM4E
SCHEMBL24459288 0.79 ACACB (0.39) MTNR1AMTNR1BALDH1A1ACACBKDM4E
SCHEMBL13136108 0.79 ACACB (0.39) MTNR1AMTNR1BALDH1A1ACACBKDM4E
SCHEMBL21513217 0.78 ACACB (0.30) ACACB
SCHEMBL16316801 0.76 ACACB (0.40) MTNR1AMTNR1BALDH1A1ACACB
SCHEMBL21496518 0.74 CA12 (0.36) ALDH1A1ACACBKDM4EMAPTTHRB
SCHEMBL19021857 0.74 HDAC4 (0.39) MTNR1AMTNR1BALDH1A1ACACB
SCHEMBL9816058 0.73
SCHEMBL14544609 0.72 ACACB (0.42) MTNR1AMTNR1BACACB
SCHEMBL11685720 0.72 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781661-B1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-03-13 EP disclosed
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators DOW GLOBAL TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC 2021-05-27 US disclosed
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC 2021-05-27 US disclosed
EP-3781661-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS Dow Global Technologies, LLC (US) 2021-02-24 EP disclosed
CN-112400014-A Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators 陶氏环球技术有限责任公司 2021-02-23 CN disclosed
WO-2019204184-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-24 WO disclosed
WO-2019204184-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS DOW GLOBAL TECHNOLOGIES LLC (US) 2019-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11525106-B2 Tetraacetyldiamine and triacetyldiamine derivatives useful as bleach activators AADAC, DLAT, NAT10 MTNR1A 3848/4885MTNR1B 3876/4885ALDH1A1 1218/4885
US-20210155877-A1 TETRAACETYLDIAMINE AND TRIACETYLDIAMINE DERIVATIVES USEFUL AS BLEACH ACTIVATORS AADAC, DLAT, NAT10 MTNR1A 3848/4885MTNR1B 3876/4885ALDH1A1 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.