Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.68 |
| ▸ | PTGIR | P43119 | 2/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.68 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | CKS1B | P61024 | 6/20 | 0.60 |
| ▸ | SKP1 | P63208 | 6/20 | 0.60 |
| ▸ | SKP2 | Q13309 | 6/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820820 | 0.90 | NR1I2 (0.68) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL3697913 | 0.88 | NR1I2 (0.70) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL29479211 | 0.88 | NR1I2 (0.70) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL2132049 | 0.88 | NR1I2 (0.70) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL5211665 | 0.88 | NR1I2 (0.67) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL18584837 | 0.88 | NR1I2 (0.66) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL19823721 | 0.87 | NR1I2 (0.72) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL22819616 | 0.84 | NR1I2 (0.65) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| Acetic Acid SCHEMBL29068588 | 0.84 | NR1I2 (0.71) | NR1I2ADORA3TBXA2RAGTR1PTGIR | |
| SCHEMBL18630467 | 0.84 | NR1I2 (0.65) | NR1I2ADORA3TBXA2RAGTR1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035352-A1 | Inhibitors of Platelet Function and Methods for Use of the Same | UNIV MICHIGAN REGENTS (US) | 2026-02-05 | — | — | US | disclosed |
| US-12269805-B2 | Inhibitors of platelet function and methods for use of the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-04-08 | — | — | US | disclosed |
| CN-113015725-B | Platelet function inhibitors and methods of use thereof | 密歇根大学董事会 | 2024-08-13 | — | — | CN | disclosed |
| US-20230140210-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
| US-20230140210-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
| EP-3781558-B1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2023-03-01 | — | — | EP | disclosed |
| US-11498905-B2 | Inhibitors of platelet function and methods for use of the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-11-15 | — | — | US | disclosed |
| US-20210363113-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| US-20210363113-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| CN-113015725-A | Platelet function inhibitors and methods of use thereof | 密歇根大学董事会 | 2021-06-22 | — | — | CN | disclosed |
| EP-3781558-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | The Regents Of The University Of Michigan (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204447-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019204447-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035352-A1 | Inhibitors of Platelet Function and Methods for Use of the Same | TFPI, MPL, PF4 | NR1I2 4716/4885ADORA3 1804/4885TBXA2R 91/4885 |
| US-12269805-B2 | Inhibitors of platelet function and methods for use of the same | TFPI, F2, TFPI2 | NR1I2 2666/4885ADORA3 2114/4885TBXA2R 22/4885 |
| US-11498905-B2 | Inhibitors of platelet function and methods for use of the same | TFPI, F2, TFPI2 | NR1I2 2666/4885ADORA3 2114/4885TBXA2R 22/4885 |
| US-20210363113-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | TFPI, F2, TFPI2 | NR1I2 2666/4885ADORA3 2114/4885TBXA2R 22/4885 |
| US-20230140210-A1 | INHIBITORS OF PLATELET FUNCTION AND METHODS FOR USE OF THE SAME | TFPI, F2, TFPI2 | NR1I2 2666/4885ADORA3 2114/4885TBXA2R 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.