Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 20/20 | 0.76 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.76 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.76 |
| ▸ | GABRA3 | P34903 | 16/20 | 0.76 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.76 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL21496862 | 0.90 | GABRA1 (0.92) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL1605144 | 0.87 | GABRA1 (0.88) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL1081801 | 0.87 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL6200327 | 0.86 | GABRA1 (0.85) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL12962761 | 0.77 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL6199608 | 0.76 | GABRA1 (0.81) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL31678897 | 0.76 | GABRA1 (0.77) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL21496858 | 0.76 | GABRA1 (0.69) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| SCHEMBL21496859 | 0.76 | GABRA1 (0.69) | GABRA1GABRG2GABRB3GABRA3GABRA5 | |
| Phosphoric Acid SCHEMBL21496860 | 0.76 | GABRA1 (0.68) | GABRA1GABRG2GABRB3GABRA3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781566-A1 | GABAA POSITIVE ALLOSTERIC MODULATOR COMPOUNDS, METHODS OF MAKING, AND USES THEREOF | Neurocycle Therapeutics, Inc. (US) | 2021-02-24 | — | — | EP | claimed |
| WO-2019204446-A1 | GABAA POSITIVE ALLOSTERIC MODULATOR COMPOUNDS, METHODS OF MAKING, AND USES THEREOF | NEUROCYCLE THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | claimed |