Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848395 | 0.88 | IDO1 (0.49) | HPGDACKR3ALDH1A1MAPTIDO1 | |
| SCHEMBL18075605 | 0.87 | ACKR3 (0.47) | ACKR3IRAK1IDO1TDO2KDM1A | |
| SCHEMBL18075603 | 0.87 | ACKR3 (0.47) | ACKR3IRAK1IDO1TDO2KDM1A | |
| SCHEMBL19858364 | 0.87 | ACKR3 (0.47) | ACKR3IRAK1IDO1TDO2KDM1A | |
| SCHEMBL21511698 | 0.85 | PTGER4 (0.51) | HPGDACKR3ALDH1A1MAPTKMT2A | |
| SCHEMBL21496879 | 0.85 | PTGER4 (0.51) | HPGDACKR3ALDH1A1MAPTKMT2A | |
| SCHEMBL13875251 | 0.85 | ACKR3 (0.54) | ACKR3KMT2AIRAK1IDO1TDO2 | |
| SCHEMBL1700213 | 0.85 | MAPT (0.51) | ACKR3ALDH1A1MAPTKMT2AIRAK1 | |
| SCHEMBL16895794 | 0.85 | HCAR3 (0.51) | HPGDALDH1A1MAPTHCAR3 | |
| SCHEMBL16895791 | 0.85 | HCAR3 (0.51) | HPGDALDH1A1MAPTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204505-A2 | K-RAS MODULATORS WITH A VINYL SULFONAMIDE MOIETY | THERAS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |