Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 5/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16421497 | 0.86 | GRM4 (0.40) | GRM4FSCN1ARSLC10A1LRRK2 | |
| SCHEMBL19881910 | 0.81 | GRM4 (0.50) | GRM4FSCN1ARSLC10A1LRRK2 | |
| SCHEMBL16421516 | 0.80 | GRM4 (0.41) | GRM4FSCN1ARSLC10A1LRRK2 | |
| SCHEMBL21497980 | 0.80 | GRM4 (0.44) | GRM4FSCN1ARRXFP1KCNH2 | |
| SCHEMBL16421447 | 0.78 | GRM4 (0.36) | GRM4FSCN1ARSLC10A1MET | |
| SCHEMBL16416950 | 0.78 | GRM4 (0.47) | GRM4FSCN1SLC10A1LRRK2MAPT | |
| SCHEMBL16417172 | 0.78 | GRM4 (0.43) | GRM4FSCN1ARSLC10A1LRRK2 | |
| SCHEMBL16421492 | 0.77 | GRM4 (0.47) | GRM4FSCN1SLC10A1LRRK2MAPT | |
| SCHEMBL16421515 | 0.77 | SLC10A1 (0.39) | GRM4FSCN1ARSLC10A1LRRK2 | |
| SCHEMBL16421502 | 0.77 | GRM4 (0.39) | GRM4FSCN1ARSLC10A1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450270-B2 | Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B | JANSSEN SCIENCES IRELAND UC (IE) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450270-B2 | Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B | GRHPR, AGXT, GLS2 | GRM4 2037/4885FSCN1 4883/4885AR 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.