Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 12/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 5/20 | 0.33 |
| ▸ | CCNH | P51946 | 4/20 | 0.33 |
| ▸ | CDK4 | P11802 | 4/20 | 0.33 |
| ▸ | CCND1 | P24385 | 4/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252299 | 0.83 | CDK2 (0.49) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL7846641 | 0.82 | CHEK1 (0.68) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL583997 | 0.80 | CHEK1 (0.55) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL7886484 | 0.78 | CDK2 (0.47) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL30758 | 0.76 | CHEK1 (0.60) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL585004 | 0.76 | CDK2 (0.51) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL10236643 | 0.76 | CDK2 (0.51) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL584764 | 0.75 | CHEK1 (0.53) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL584858 | 0.75 | CHEK1 (0.59) | CDK2CCNA2CCNA1CHEK1PDE10A | |
| SCHEMBL20974 | 0.75 | CHEK1 (0.59) | CDK2CCNA2CCNA1CHEK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027236-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |