Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19299366 | 1.00 | TDP1 (0.36) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19298789 | 0.98 | PDK2 (0.36) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL15213734 | 0.98 | PDK2 (0.36) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19530900 | 0.97 | PDK2 (0.36) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19773250 | 0.97 | PDK2 (0.36) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL16810806 | 0.95 | PDK2 (0.35) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL25496446 | 0.94 | PDK2 (0.38) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19298801 | 0.94 | PDK2 (0.38) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL23449546 | 0.94 | PDK2 (0.38) | TDP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19299367 | 0.94 | PDK2 (0.38) | TDP1KDM4EMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11538996-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3419960-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-10454041-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10454041-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | TDP1 1263/4885KDM4E 4126/4885MAPT 3512/4885 |
| US-11538996-B2 | Materials for organic electroluminescent devices | RIF1, INTS9, LEF1 | TDP1 1263/4885KDM4E 4126/4885MAPT 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.