Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DHPS | P49366 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499325 | 0.88 | DHODH (0.56) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21468548 | 0.86 | MAPT (0.76) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499390 | 0.86 | SMN1; SMN2 (0.54) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499302 | 0.85 | SMN1; SMN2 (0.53) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21468526 | 0.84 | DHODH (0.71) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499304 | 0.84 | MAPT (0.60) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499364 | 0.83 | MAPT (0.59) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499303 | 0.83 | DHODH (0.59) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21499352 | 0.81 | PLAU (0.58) | DHODHALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL23090384 | 0.81 | DHODH (0.56) | DHODHALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | SOUTHERN RESEARCH INSTITUTE (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450263-B2 | Benzo annulenes as antiviral agents | MAVS, ZC3HAV1, GABBR1 | DHODH 593/4885ALDH1A1 187/4885SMN1; SMN2 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.