Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261931 | 0.79 | DRD2 (0.53) | DRD2PDPK1IDO1SIGMAR1CYP11B2 | |
| SCHEMBL18408553 | 0.79 | DRD2 (0.53) | DRD2PDPK1IDO1SIGMAR1CYP11B2 | |
| SCHEMBL14555196 | 0.78 | HTR2A (0.52) | DRD2PDPK1IDO1HTR2AHTR2C | |
| Methyl Alcohol SCHEMBL14815562 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1CYP11B2HTR2A | |
| SCHEMBL13198513 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1SIGMAR1CYP11B2 | |
| SCHEMBL14169776 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1CYP11B2HTR2A | |
| SCHEMBL6230330 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1HTR2A | |
| SCHEMBL14367929 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1CYP11B2HTR2A | |
| SCHEMBL19419825 | 0.76 | DRD2 (0.50) | DRD2PDPK1IDO1CYP11B2HTR2A | |
| SCHEMBL186363 | 0.74 | HTR2A (0.57) | DRD2PDPK1IDO1SIGMAR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204354-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |