Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 8/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177047 | 1.00 | CCKAR (0.48) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL2150823 | 0.96 | PTGS2 (0.48) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL18292062 | 0.94 | CCKAR (0.47) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL11988400 | 0.92 | PTGS2 (0.46) | PTGS2RPA1PTGS1 | |
| SCHEMBL16015756 | 0.92 | RPA1 (0.45) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL12177044 | 0.91 | MALT1 (0.54) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL2150077 | 0.91 | MALT1 (0.54) | CCKARPTGS2RPA1PTGS1 | |
| SCHEMBL11988923 | 0.91 | PTGS2 (0.50) | PTGS2RPA1PTGS1 | |
| SCHEMBL11988928 | 0.91 | PTGS2 (0.50) | PTGS2RPA1PTGS1 | |
| SCHEMBL12177048 | 0.90 | RPA1 (0.51) | CCKARPTGS2RPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170231960-A1 | METHODS OF TREATING OR PREVENTING MULTIPLE SCLEROSIS | TORAY INDUSTRIES, INC. (JP) | 2017-08-17 | — | — | US | disclosed |
| US-9226924-B2 | Methods of treating or preventing neuropathic pain | TORAY INDUSTRIES, INC. (JP) | 2016-01-05 | — | — | US | disclosed |
| EP-2565184-B1 | THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE | TORAY INDUSTRIES (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-2565184-B1 | THERAPEUTIC AGENT AND PREVENTATIVE AGENT FOR ALZHEIMER'S DISEASE | TORAY INDUSTRIES (JP) | 2015-12-30 | — | — | EP | disclosed |
| EP-2554541-B1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA | TORAY INDUSTRIES (JP) | 2015-12-09 | — | — | EP | disclosed |
| EP-2554541-B1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR FIBROMYALGIA | TORAY INDUSTRIES (JP) | 2015-12-09 | — | — | EP | disclosed |
| US-20150105430-A1 | METHODS OF TREATING OR PREVENTING NEUROPATHIC PAIN | TORAY INDUSTREIS INC (JP) | 2015-04-16 | — | — | US | disclosed |
| US-8957094-B2 | Therapeutic agent or prophylactic agent for fibromyalgia | TORAY INDUSTRIES, INC. (JP) | 2015-02-17 | — | — | US | disclosed |
| US-8957094-B2 | Therapeutic agent or prophylactic agent for fibromyalgia | TORAY INDUSTRIES, INC. (JP) | 2015-02-17 | — | — | US | disclosed |
| EP-2341047-B1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-20120270906-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2012-10-25 | — | — | US | disclosed |
| US-8247569-B2 | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8247569-B2 | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8247569-B2 | Cyclohexane derivative and pharmaceutical use thereof | TORAY INDUSTRIES, INC. (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2341047-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-2341047-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Toray Industries, Inc. (JP) | 2011-07-06 | — | — | EP | disclosed |
| WO-2010050577-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270906-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | CNR2, CNR1, TRPV1 | CCKAR 31/4885PTGS2 238/4885RPA1 4811/4885 |
| US-20170231960-A1 | METHODS OF TREATING OR PREVENTING MULTIPLE SCLEROSIS | MSR1, C5, MGMT | CCKAR 1390/4885PTGS2 1530/4885RPA1 4516/4885 |
| US-20110201650-A1 | CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | CNR2, TRPV1, OPRL1 | CCKAR 55/4885PTGS2 93/4885RPA1 4717/4885 |
| US-20150105430-A1 | METHODS OF TREATING OR PREVENTING NEUROPATHIC PAIN | CACNB2, CACNG2, SCN2A | CCKAR 413/4885PTGS2 125/4885RPA1 4790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.