Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.52 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890703 | 1.00 | DGAT2 (0.52) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL22752210 | 1.00 | DGAT2 (0.52) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL21501062 | 1.00 | DGAT2 (0.52) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL17003710 | 1.00 | DGAT2 (0.52) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL17002715 | 1.00 | DGAT2 (0.52) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL28885393 | 0.90 | DGAT2 (0.48) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL22887359 | 0.86 | TSHR (0.55) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL24411136 | 0.86 | TSHR (0.55) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL24890704 | 0.84 | DGAT2 (0.44) | DGAT2MGAT2ALDH1A1HPGDTSHR | |
| SCHEMBL17003109 | 0.84 | DGAT2 (0.44) | DGAT2MGAT2ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204477-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-10-24 | — | — | WO | disclosed |