Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 17/20 | 0.56 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496357 | 0.90 | IDO1 (0.66) | IDO1 | |
| SCHEMBL21496355 | 0.90 | IDO1 (0.66) | IDO1 | |
| SCHEMBL21504262 | 0.82 | IDO1 (0.61) | IDO1 | |
| SCHEMBL24117945 | 0.78 | IDO1 (0.67) | IDO1 | |
| SCHEMBL21496344 | 0.78 | IDO1 (0.67) | IDO1 | |
| SCHEMBL21496343 | 0.78 | IDO1 (0.67) | IDO1 | |
| SCHEMBL30056917 | 0.77 | IDO1 (0.69) | IDO1 | |
| SCHEMBL21504300 | 0.77 | IDO1 (0.61) | IDO1 | |
| SCHEMBL21504021 | 0.77 | IDO1 (0.70) | IDO1 | |
| SCHEMBL30057094 | 0.75 | IDO1 (0.75) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204180-A1 | NOVEL [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2019-10-24 | — | — | WO | disclosed |