Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 12/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26783751 | 1.00 | IDO1 (0.55) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL21504288 | 0.78 | IDO1 (0.63) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL21504175 | 0.78 | IDO1 (0.63) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL21496295 | 0.78 | IDO1 (0.63) | IDO1MAPTRECQLMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL23271121 | 0.77 | IDO1 (0.62) | IDO1MAPTRECQLMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL23572604 | 0.77 | IDO1 (0.62) | IDO1MAPTRECQLMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL21496293 | 0.77 | IDO1 (0.62) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL21504150 | 0.77 | IDO1 (0.65) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL26783194 | 0.76 | IDO1 (0.47) | IDO1MAPTRECQLMEN1CYP1A2 | |
| SCHEMBL26783502 | 0.73 | IDO1 (0.44) | IDO1MAPTRECQLMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204180-A1 | NOVEL [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2019-10-24 | — | — | WO | disclosed |