Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714277 | 0.90 | APP (0.55) | APPFFAR1MAPTNPC1RAB9A | |
| SCHEMBL21008661 | 0.85 | ESR2 (0.33) | FFAR1EGLN1EGLN3 | |
| SCHEMBL3836703 | 0.82 | APP (0.50) | APPFFAR1MAPTNPC1RAB9A | |
| SCHEMBL18411594 | 0.82 | SLC18A3 (0.54) | MAPTNPC1RAB9AKDM4EKMT2A | |
| SCHEMBL10091187 | 0.81 | ESR2 (0.53) | APPFFAR1MAPTNPC1RAB9A | |
| SCHEMBL10476961 | 0.81 | APP (0.48) | APPFFAR1MAPTNPC1RAB9A | |
| SCHEMBL21556845 | 0.79 | ESR2 (0.46) | NPC1RAB9ASLC18A3SIGMAR1 | |
| SCHEMBL20811532 | 0.79 | APP (0.35) | APPFFAR1MAPTNPC1RAB9A | |
| SCHEMBL21338798 | 0.79 | NPC1 (0.59) | NPC1RAB9ASLC18A3SIGMAR1 | |
| SCHEMBL20169911 | 0.79 | NPC1 (0.59) | NPC1RAB9ASLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140369-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |