Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29969762 | 1.00 | OPRK1 (0.60) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL21513246 | 0.92 | OPRK1 (0.52) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL29968880 | 0.92 | OPRK1 (0.52) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL21513421 | 0.87 | OPRK1 (0.46) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL29968794 | 0.87 | OPRK1 (0.46) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL21513235 | 0.86 | OPRK1 (0.46) | OPRK1HRH3 | |
| SCHEMBL21513426 | 0.86 | OPRK1 (0.44) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL29970932 | 0.86 | OPRK1 (0.44) | OPRK1HRH3L3MBTL3L3MBTL1L3MBTL4 | |
| SCHEMBL2711135 | 0.85 | HTT (0.43) | OPRK1 | |
| SCHEMBL21513238 | 0.80 | OPRK1 (0.48) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327877-A2 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRad Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-4327877-A2 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRad Therapeutics, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-3784671-B1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3784671-B1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS INC (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2019201283-A1 | DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY | XRAD THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |