SCHEMBL21514740

SCHEMBL21514740

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(NSO)cc1)c1csc(OC(=O)C(C)(C)C)n1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 17/20 0.76
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19775388 0.87 PTPRB (0.76) PTPRBALDH1A1
SCHEMBL468261 0.86 PTPRB (1.00) PTPRB
SCHEMBL468263 0.86 PTPRB (1.00) PTPRB
SCHEMBL28828106 0.86 PTPRB (0.75) PTPRBALDH1A1
SCHEMBL19493255 0.78 PTPRB (0.84) PTPRB
SCHEMBL8828818 0.76 PTPRB (0.80) PTPRB
SCHEMBL13638110 0.76 PTPRB (0.80) PTPRB
SCHEMBL19575834 0.74 PTPRB (0.78) PTPRB
SCHEMBL19775410 0.72 PTPRB (0.74) PTPRBALDH1A1
SCHEMBL20171370 0.72 PTPRB (0.73) PTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2967066-B1 COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES AERPIO THERAPEUTICS INC (US) 2019-10-23 EP disclosed