Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21518246 | 0.93 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL24645816 | 0.86 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL24699769 | 0.86 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL17230163 | 0.85 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL19772702 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL24807806 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL22927913 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL18513238 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL15334243 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 | |
| SCHEMBL18972833 | 0.84 | LMNA (0.64) | LMNAKMT2AALDH1A1POLBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558323-A1 | SPECIFIC TLR4 ANTAGONIST IN THE TREATMENT OF MULTIPLE MYELOMA | Etablissement Français du Sang (FR) | 2019-10-30 | — | — | EP | disclosed |