SCHEMBL2152131

SCHEMBL2152131

COC(=O)C(C)OC(C)OC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.42
CA14 Q9ULX7 2/20 0.39
CA12 O43570 1/20 0.37
ALDH1A1 P00352 3/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP7 P55210 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4633092 0.86 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL6651376 0.81 SMN1; SMN2 (0.44) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL6651370 0.81 SMN1; SMN2 (0.44) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL31069720 0.81 SMN1; SMN2 (0.44) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL16377936 0.80
SCHEMBL35974 0.80
SCHEMBL7580898 0.80 SMN1; SMN2 (0.48) SMN1; SMN2CA14CA12ALDH1A1KMT2A
SCHEMBL2664131 0.80
SCHEMBL6115071 0.76 TP53 (0.38) KMT2A
SCHEMBL25144910 0.75 SMN1; SMN2 (0.39) SMN1; SMN2CA14CA12ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240125-B2 FLUORINE CONTAINING VINYL ETHERS 3M INNOVATIVE PROPERTIES CO (US) 2016-04-20 EP disclosed
EP-1616849-B1 Process for the preparation of fluorine containing vinyl ethers 3M INNOVATIVE PROPERTIES CO (US) 2011-07-06 EP disclosed
EP-1616849-A2 Process for the preparation of fluorine containing vinyl ethers DYNEON LLC (US) 2006-01-18 EP disclosed
EP-1240125-B1 FLUORINE CONTAINING VINYL ETHERS DYNEON LLC (US) 2005-11-02 EP disclosed
EP-1240125-A1 FLUORINE CONTAINING VINYL ETHERS DYNEON LLC (US) 2002-09-18 EP disclosed
US-6255536-B1 FLOURINATING A 2-ALKOXY PROPIONATE MOIETY THAT MAY BE PARTIALLY HALOGENATED TO PROVIDE A PERFLUORINATED INTERMEDIATE, CONVERTING TO ITS ACID METAL SALT, AND THEN TO ITS PERFLUOROVINYL ETHER DYNEON LLC 2001-07-03 US disclosed
WO-2001046107-A1 FLUORINE CONTAINING VINYL ETHERS DYNEON LLC (US) 2001-06-28 WO disclosed