Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 12/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152511 | 0.93 | GABRA2 (0.73) | CCKARGABRA2GABRB2 | |
| SCHEMBL2152335 | 0.89 | CCKAR (0.66) | CCKARGABRA2GABRB2 | |
| SCHEMBL2152521 | 0.84 | GABRA2 (0.75) | CCKARGABRA2GABRB2 | |
| SCHEMBL2152790 | 0.82 | CCKAR (0.75) | CCKAR | |
| SCHEMBL2152420 | 0.81 | CCKAR (0.65) | CCKARGABRA2GABRB2 | |
| SCHEMBL3133542 | 0.80 | CCKAR (0.63) | CCKARGABRA2GABRB2 | |
| SCHEMBL2152217 | 0.80 | CCKAR (0.86) | CCKAR | |
| SCHEMBL2152132 | 0.80 | CCKAR (0.66) | CCKARGABRA2GABRB2 | |
| Trifluoroacetic Acid SCHEMBL2203298 | 0.79 | CCKAR (0.70) | CCKAR | |
| SCHEMBL3131008 | 0.78 | CCKAR (1.00) | CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010519-B1 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2011-07-06 | — | — | EP | disclosed |