SCHEMBL2152286

SCHEMBL2152286

CCC(C)=C(C=CC(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
HCAR2 Q8TDS4 7/20 0.40
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALOX15 P16050 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
FFAR3 O14843 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23094733 0.82 FFAR3 (0.33) ALDH1A1TDP1FFAR3
Fumaric Acid SCHEMBL7512236 0.79 TSHR (0.43) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL11518390 0.76 TDP1 (0.36) ALDH1A1TDP1FFAR3
SCHEMBL4610288 0.74 HCAR2 (0.34) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL8408373 0.72 FFAR3 (0.59) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL8408375 0.72 FFAR3 (0.59) TSHRTP53EGLN1EGLN3HCAR2
Maleic Acid SCHEMBL10381000 0.72 FFAR3 (0.67) TSHRTP53EGLN1EGLN3HCAR2
Fumaric Acid SCHEMBL10381001 0.72 FFAR3 (0.67) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL14860699 0.71 TSHR (0.45) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL14860697 0.71 TSHR (0.45) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2011604-B2 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2020-12-09 EP claimed
US-8382932-B2 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2013-02-26 US claimed
EP-2011604-B1 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2011-07-06 EP claimed
US-20100170635-A1 Method for Blocking a Lens Blank, Adhesive Composition and Use of the Latter in Lens Blocking SATISLOH AG (CH) 2010-07-08 US claimed
WO-2009003660-A1 METHOD FOR BLOCKING A LENS BLANK, ADHESIVE COMPOSITION AND USE OF THE LATTER IN LENS BLOCKING SATISLOH AG (CH) 2009-01-08 WO claimed
EP-2011604-A1 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking Satisloh AG (CH) 2009-01-07 EP claimed
EP-3863843-B1 LAMINATION MACHINE AND METHOD WITH AN IMPROVED BLOCKER SUPPORT ESSILOR INT (FR) 2024-03-27 EP disclosed
US-20210387303-A1 LAMINATION MACHINE AND METHOD WITH AN IMPROVED BLOCKER SUPPORT ESSILOR INTERNATIONAL (FR) 2021-12-16 US disclosed
EP-3863843-A1 LAMINATION MACHINE AND METHOD WITH AN IMPROVED BLOCKER SUPPORT ESSILOR INTERNATIONAL (FR) 2021-08-18 EP disclosed
EP-2011604-B2 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2020-12-09 EP disclosed
EP-3636422-A1 LAMINATION MACHINE AND METHOD WITH AN IMPROVED BLOCKER SUPPORT ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2020-04-15 EP disclosed
US-8382932-B2 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2013-02-26 US disclosed
EP-2011604-B1 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking SATISLOH AG (CH) 2011-07-06 EP disclosed
US-20100170635-A1 Method for Blocking a Lens Blank, Adhesive Composition and Use of the Latter in Lens Blocking SATISLOH AG (CH) 2010-07-08 US disclosed
WO-2009003660-A1 METHOD FOR BLOCKING A LENS BLANK, ADHESIVE COMPOSITION AND USE OF THE LATTER IN LENS BLOCKING SATISLOH AG (CH) 2009-01-08 WO disclosed
EP-2011604-A1 Method for blocking a lens blank, adhesive composition and use of the latter in lens blocking Satisloh AG (CH) 2009-01-07 EP disclosed