Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488967 | 0.89 | ALDH1A1 (0.39) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522842 | 0.83 | CYP2D6 (0.41) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522919 | 0.82 | CYP2D6 (0.40) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522881 | 0.82 | CYP2D6 (0.40) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL20165987 | 0.82 | CYP2D6 (0.40) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522903 | 0.82 | CYP2D6 (0.40) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL31126799 | 0.81 | CYP2D6 (0.39) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522933 | 0.80 | CYP2D6 (0.39) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL21522856 | 0.80 | CYP2D6 (0.39) | CYP2D6ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL21522890 | 0.80 | CYP2D6 (0.39) | CYP2D6ALDH1A1NPSR1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2020-09-09 | — | — | EP | disclosed |
| US-10654946-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-05-19 | — | — | US | disclosed |
| US-20190330388-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-10-31 | — | — | US | disclosed |