Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.80 |
| ▸ | USP2 | O75604 | 4/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.80 |
| ▸ | ALPL | P05186 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | ALPI | P09923 | 1/20 | 0.80 |
| ▸ | ALPG | P10696 | 1/20 | 0.80 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.80 |
| ▸ | HAT1 | O14929 | 4/20 | 0.74 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | CASP1 | P29466 | 2/20 | 0.74 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.74 |
| ▸ | CASP7 | P55210 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | TST | Q16762 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457737 | 0.86 | MEN1 (0.72) | MEN1KMT2AUSP2RXFP1ALPL | |
| SCHEMBL23965851 | 0.86 | MEN1 (0.72) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL7706 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL7707 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL14146654 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL5899262 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL2420598 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL9609755 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL12979917 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL | |
| Riboflavin SCHEMBL13373926 | 0.85 | MEN1 (1.00) | MEN1KMT2AUSP2RXFP1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457682-B2 | Small molecules that bind MR1 | THE UNIVERSITY OF CHICAGO | 2019-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457682-B2 | Small molecules that bind MR1 | MICA, HLA-DRB1, CD74 | MEN1 396/4885KMT2A 4029/4885USP2 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.