SCHEMBL21528652

SCHEMBL21528652

CC(C)CC(Cc1ccc(-c2ccc(C(C)(C)C)cc2)cc1)Nc1ccc(C(=O)NCCC(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GCGR P47871 17/20 0.63
ADCY6 O43306 6/20 0.63
ADCY3 O60266 6/20 0.63
ADCY9 O60503 6/20 0.63
ADCY5 O95622 6/20 0.63
ADCY8 P40145 6/20 0.63
ADCY7 P51828 6/20 0.63
ADCY2 Q08462 6/20 0.63
ADCY1 Q08828 6/20 0.63
ADCY4 Q8NFM4 6/20 0.63
NR1H4 Q96RI1 2/20 0.50
EPHX2 P34913 1/20 0.50
GCG P01275 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21528649 1.00 GCGR (0.63) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21529041 0.89 GCGR (0.58) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21529043 0.89 GCGR (0.58) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528726 0.89 GCGR (0.66) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528723 0.89 GCGR (0.66) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528960 0.87 GCGR (0.60) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528961 0.87 GCGR (0.60) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21530800 0.85 GCGR (0.57) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21530797 0.85 GCGR (0.57) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL2657984 0.84 GCGR (0.64) GCGRADCY6ADCY3ADCY9ADCY5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384060-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2022-07-12 US claimed
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF GLP1R, IAPP, GPR119 GCGR 4/4885ADCY6 68/4885ADCY3 25/4885
US-11384060-B2 Amide compounds and use thereof GLP1R, IAPP, GPR119 GCGR 4/4885ADCY6 68/4885ADCY3 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.