Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.89 |
| ▸ | RAB9A | P51151 | 5/20 | 0.89 |
| ▸ | NPC1 | O15118 | 4/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.89 |
| ▸ | PKM | P14618 | 2/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.77 |
| ▸ | ESRRG | P62508 | 2/20 | 0.77 |
| ▸ | MPO | P05164 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20328281 | 1.00 | MAPT (0.89) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1563653 | 0.94 | MAPT (1.00) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6634490 | 0.94 | MAPT (1.00) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL1563651 | 0.94 | MAPT (1.00) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL25424222 | 0.90 | MAPT (0.82) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12791111 | 0.90 | HDAC8 (0.81) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL25424218 | 0.90 | MAPT (0.82) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12937886 | 0.88 | HDAC8 (0.74) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL13568982 | 0.87 | RAB9A (0.87) | MAPTKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL12937892 | 0.87 | HDAC8 (0.77) | MAPTKMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190336610-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | GUBRA APS (DK) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190336610-A1 | GLUCOSE-SENSITIVE PEPTIDE HORMONES | IAPP, GCG, VIP | MAPT 3670/4885KMT2A 3303/4885RAB9A 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.