Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 15/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519573 | 1.00 | PARP1 (1.00) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL29519388 | 0.98 | PARP1 (0.96) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL5496376 | 0.98 | PARP1 (0.96) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL14027180 | 0.77 | PARP1 (0.62) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL307689 | 0.77 | PARP1 (0.62) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL832144 | 0.75 | PARP1 (0.60) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL12463821 | 0.75 | PARP1 (0.60) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL31743106 | 0.75 | PARP1 (0.60) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL2172575 | 0.75 | PARP1 (1.00) | PARP1TDP1RECQLALDH1A1HSD17B10 | |
| SCHEMBL29492688 | 0.75 | PARP1 (1.00) | PARP1TDP1RECQLALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180042919-A1 | PARP Inhibitors for the Treatment of Major Depressive Disorder and Related Conditions | EAST TENNESSEE STATE UNIVERSITY RESEARCH FOUNDATION | 2018-02-15 | — | — | US | claimed |
| US-20120022026-A1 | METHOD OF TREATING CANCER | ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) | 2012-01-26 | — | — | US | claimed |
| EP-2387403-A1 | METHOD OF TREATING CANCER | Academisch Medisch Centrum bij de Universiteit van Amsterdam (NL) | 2011-11-23 | — | — | EP | claimed |
| US-20110253692-A1 | Electrical heater for vehicle windshields and windows | SCHAUBLE RICHARD EGON | 2011-10-20 | — | — | US | claimed |
| WO-2010082821-A1 | METHOD OF TREATING CANCER | ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2010-07-22 | — | — | WO | claimed |
| WO-2010082813-A1 | METHOD OF TREATING CANCER | ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2010-07-22 | — | — | WO | claimed |
| EP-1009404-A4 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | OCTAMER INC (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2001022960-A1 | TREATMENT OF CARBON MONOXIDE POISONING | CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY DOING BUSINESS AS CAROLINAS MEDICAL CENTER (US) | 2001-04-05 | — | — | WO | claimed |
| EP-1009404-A1 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | Octamer, Inc. (US) | 2000-06-21 | — | — | EP | claimed |
| US-5908861-A | Methods for treating inflammation and inflammatory disease using pADPRT inhibitors | OCTAMER, INC. (US) | 1999-06-01 | — | — | US | claimed |
| WO-1998051307-A1 | METHODS FOR TREATING INFLAMMATION, INFLAMMATORY DISEASES, ARTHRITIS AND STROKE USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | claimed |
| WO-1998051308-A1 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | claimed |
| US-20250381221-A1 | Compositions and Methods for Treating Cancer | IN8BIO INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | LANTERN PHARMA INC. (US) | 2025-05-22 | — | — | US | disclosed |
| EP-4554683-A2 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | Lantern Pharma Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| US-20240299322-A1 | TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES | LANTERN PHARMA INC. (US) | 2024-09-12 | — | — | US | disclosed |
| US-5908861-A | Methods for treating inflammation and inflammatory disease using pADPRT inhibitors | OCTAMER, INC. (US) | 1999-06-01 | — | — | US | disclosed |
| WO-1998051307-A1 | METHODS FOR TREATING INFLAMMATION, INFLAMMATORY DISEASES, ARTHRITIS AND STROKE USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | disclosed |
| US-5177075-A | Antitumor agents | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0355750-A1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER-LAMBERT COMPANY (US) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | PARP1, PARP2, PARP3 | PARP1 1/4885TDP1 341/4885RECQL 2523/4885 |
| US-20240299322-A1 | TREATING CANCERS WITH COMBINATIONS OF PARP INHIBITOR AND ACYLFULVENES | PARP1, PARP2, PARP11 | PARP1 1/4885TDP1 284/4885RECQL 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.