SCHEMBL2153291

SCHEMBL2153291

CCCCCc1c(O)n2c(nc1=O)[nH]c1ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.59
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
RPA1 P27694 1/20 0.48
KDM4E B2RXH2 7/20 0.47
ALDH1A1 P00352 7/20 0.47
HPGD P15428 6/20 0.47
HSD17B10 Q99714 5/20 0.47
GAA P10253 3/20 0.47
LMNA P02545 3/20 0.45
HTT P42858 3/20 0.45
APAF1 O14727 1/20 0.45
NOD2 Q9HC29 1/20 0.45
POLB P06746 2/20 0.43
PDE2A O00408 1/20 0.43
PDE6D O43924 1/20 0.43
PDE8A O60658 1/20 0.43
PDE5A O76074 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153297 0.78 SMN1; SMN2 (0.93) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL23295721 0.71 RAB9A (0.51) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL3548318 0.70 KMT2A (0.47) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL23335565 0.70 KDM4E (0.53) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL23295641 0.69 RAB9A (0.49) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL31170931 0.68 CDC25B (0.49) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL824371 0.68 CDC25B (0.49) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL23295685 0.68 RAB9A (0.48) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL23335527 0.68 RAB9A (0.78) SMN1; SMN2MEN1KMT2ARAB9ANPC1
SCHEMBL23335661 0.68 RAB9A (0.47) SMN1; SMN2MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981207-B2 Dye compound and ink containing dye compound CANON KABUSHIKI KAISHA (JP) 2011-07-19 US disclosed
US-20090293765-A1 DYE COMPOUND AND INK CONTAINING DYE COMPOUND CANON KABUSHIKI KAISHA (JP) 2009-12-03 US disclosed