⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428568 | 1.00 | — | — | |
| SCHEMBL7052848 | 1.00 | — | — | |
| SCHEMBL3731262 | 0.75 | — | — | |
| SCHEMBL9106 | 0.75 | — | — | |
| SCHEMBL13020895 | 0.75 | — | — | |
| SCHEMBL12310407 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL13020896 | 0.75 | — | — | |
| SCHEMBL7880866 | 0.75 | — | — | |
| SCHEMBL346676 | 0.75 | — | — | |
| SCHEMBL10760 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458584-B1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | CONSEJO SUPERIOR INVESTIGACION (ES) | 2021-07-07 | — | — | EP | disclosed |
| US-10683493-B2 | Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2020-06-16 | — | — | US | disclosed |
| US-20190194638-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | TECHNICAL UNIVERSITY OF DARMSTADT (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-3458584-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | Consejo Superior De Investigaciones Científicas (ES) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017198717-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2017-11-23 | — | — | WO | disclosed |
| EP-1832658-B1 | Method for producing optically acitve secondary alcohols from ketones employing an adsorbed carbonyl reductase activity | WACKER CHEMIE AG (DE) | 2011-07-06 | — | — | EP | disclosed |
| US-20070212766-A1 | METHOD FOR THE ENZYMATIC PRODUCTION OF CHIRAL ALCOHOLS | WACKER CHEMIE AG | 2007-09-13 | — | — | US | disclosed |
| EP-1832658-A1 | Method for producing optically acitve secondary alcohols from ketones employing an adsorbed carbonyl reductase activity | Wacker Chemie AG (DE) | 2007-09-12 | — | — | EP | disclosed |