SCHEMBL2153308

SCHEMBL2153308

O=C(C=Cc1ccccc1)C(=O)/C=C/c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.73
HDAC3 O15379 2/20 0.73
HDAC4 P56524 2/20 0.73
HDAC1 Q13547 2/20 0.73
HDAC2 Q92769 2/20 0.73
HDAC8 Q9BY41 2/20 0.73
HDAC6 Q9UBN7 2/20 0.73
PLIN1 O60240 2/20 0.73
LMNA P02545 2/20 0.73
RECQL P46063 2/20 0.73
PLIN5 Q00G26 2/20 0.73
ABHD5 Q8WTS1 2/20 0.73
ALDH1A1 P00352 2/20 0.73
F3 P13726 2/20 0.73
TNKS O95271 1/20 0.73
HCAR2 Q8TDS4 1/20 0.73
HDAC7 Q8WUI4 1/20 0.73
HDAC10 Q969S8 1/20 0.73
HDAC11 Q96DB2 1/20 0.73
TNKS2 Q9H2K2 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1034506 1.00 MAPT (0.73) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1034505 1.00 MAPT (0.73) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1620755 0.90 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL11560289 0.90 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL7060516 0.90 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL28109000 0.90 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL1620754 0.90 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL2474967 0.89 MAPT (0.59) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL27737044 0.88 MAPT (0.64) MAPTHDAC3HDAC4HDAC1HDAC2
Potassium Ion SCHEMBL9145058 0.86 MAPT (0.61) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820108-B2 Marker detection method and apparatus to monitor drug compliance UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-10-26 US claimed
US-20040081587-A1 Marker detection method and apparatus to monitor drug compliance MELKER RICHARD J (US) 2004-04-29 US claimed
EP-1227753-A1 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-08-07 EP claimed
WO-2001034024-A9 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIV FLORIDA (US) 2002-05-10 WO claimed
WO-2001034024-A1 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2001-05-17 WO claimed
US-9233049-B2 Pharmaceutical identification PURDUE PHARMA L.P. (US) 2016-01-12 US disclosed
US-9226874-B2 Pharmaceutical identification PURDUE PHARMA L.P. (US) 2016-01-05 US disclosed
EP-1227753-B1 MARKER DETECTION APPARATUS TO MONITOR DRUG COMPLIANCE UNIV FLORIDA (US) 2011-07-06 EP disclosed
US-7820108-B2 Marker detection method and apparatus to monitor drug compliance UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-10-26 US disclosed
EP-1555996-A2 PHARMACEUTICAL IDENTIFICATION Euro-Celtique (LU) 2005-07-27 EP disclosed
US-20040166063-A1 marking a pharmaceutical product, container or pharmaceutical packaging system with a scent to establish the identity and/or source of the pharmaceutical PURDUE PHARMA L.P. 2004-08-26 US disclosed
WO-2004041328-A2 PHARMACEUTICAL IDENTIFICATION EURO-CELTIQUE S.A. (LU) 2004-05-21 WO disclosed
US-20040081587-A1 Marker detection method and apparatus to monitor drug compliance MELKER RICHARD J (US) 2004-04-29 US disclosed
EP-1227753-A1 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2002-08-07 EP disclosed
WO-2001034024-A9 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIV FLORIDA (US) 2002-05-10 WO disclosed
WO-2001034024-A1 MARKER DETECTION METHOD AND APPARATUS TO MONITOR DRUG COMPLIANCE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2001-05-17 WO disclosed