SCHEMBL21533447

SCHEMBL21533447

O=C(CCCOc1ccc(Cl)c(Cl)c1)Nc1ncc(Cl)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SETD1B Q9UPS6 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21533448 0.90 SETD1B (0.80) SETD1B
SCHEMBL21533615 0.90 SETD1B (0.64) SETD1B
SCHEMBL21533594 0.90 SETD1B (0.67) SETD1B
SCHEMBL21533556 0.88 SETD1B (0.82) SETD1B
SCHEMBL21533534 0.88 SETD1B (0.69) SETD1B
SCHEMBL21533493 0.84 ALDH1A1 (0.62)
SCHEMBL21533505 0.84 SETD1B (0.72) SETD1B
SCHEMBL21533449 0.81 SETD1B (0.77) SETD1B
SCHEMBL21533446 0.81 SETD1B (0.80) SETD1B
SCHEMBL21533614 0.79 SETD1B (1.00) SETD1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190330167-A1 ACTIVATORS OF HIV LATENCY THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330167-A1 ACTIVATORS OF HIV LATENCY NFATC1, EP300, CD69 SETD1B 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.