Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533536 | 0.92 | MAPT (0.53) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL21533597 | 0.91 | MAPT (0.52) | MAPTTP53SMN1; SMN2POLBPANK3 | |
| SCHEMBL21533596 | 0.90 | MAPT (0.58) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL21533462 | 0.89 | MAPT (0.55) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL21533627 | 0.87 | KDR (0.51) | MAPTTP53SMN1; SMN2POLBPANK3 | |
| SCHEMBL21533587 | 0.86 | MAPT (0.54) | MAPTTP53SMN1; SMN2POLBCCR2 | |
| SCHEMBL21533586 | 0.83 | MAPT (0.61) | MAPTTP53SMN1; SMN2POLBPANK3 | |
| SCHEMBL21533593 | 0.83 | MAPT (0.53) | MAPTTP53SMN1; SMN2POLBPANK3 | |
| SCHEMBL21533457 | 0.79 | KDR (0.49) | MAPTTP53SMN1; SMN2POLBPANK3 | |
| SCHEMBL21533540 | 0.77 | RAB9A (0.57) | MAPTTP53SMN1; SMN2PANK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330167-A1 | ACTIVATORS OF HIV LATENCY | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330167-A1 | ACTIVATORS OF HIV LATENCY | NFATC1, EP300, CD69 | MAPT 2314/4885TP53 3351/4885SMN1; SMN2 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.