Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.68 |
| ▸ | CDK9 | P50750 | 13/20 | 0.68 |
| ▸ | CDK7 | P50613 | 5/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.68 |
| ▸ | CCNH | P51946 | 4/20 | 0.68 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.68 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.68 |
| ▸ | CCNE2 | O96020 | 6/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141906 | 0.88 | CDK2 (0.88) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL23664185 | 0.86 | CDK2 (0.73) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL17148365 | 0.85 | CDK2 (0.81) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL17141863 | 0.84 | CDK2 (0.70) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL4928924 | 0.83 | CDK2 (0.81) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL17141909 | 0.83 | CDK2 (0.78) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL24758393 | 0.82 | CDK2 (0.83) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL17148368 | 0.82 | CDK2 (0.76) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL4996384 | 0.81 | CDK2 (0.79) | CDK2CDK9CDK7CCNT1CCNH | |
| SCHEMBL17141895 | 0.81 | CDK2 (1.00) | CDK2CDK9CDK7CCNT1CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330218-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330218-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK2 8/4885CDK9 3/4885CDK7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.