Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538847 | 0.94 | GPR119 (0.39) | GPR119PARP10PARP15PIK3CAMTOR | |
| SCHEMBL15538849 | 0.94 | GPR119 (0.39) | GPR119PARP10PARP15PIK3CAMTOR | |
| SCHEMBL15539044 | 0.92 | GPR119 (0.40) | GPR119PARP10PARP15PIK3CAMTOR | |
| SCHEMBL15539054 | 0.92 | GPR119 (0.40) | GPR119PARP10PARP15PIK3CAMTOR | |
| SCHEMBL15539004 | 0.87 | CNR2 (0.40) | GPR119PARP10PARP15CNR2MET | |
| SCHEMBL15538994 | 0.87 | CNR2 (0.40) | GPR119PARP10PARP15CNR2MET | |
| SCHEMBL15538856 | 0.84 | GPR119 (0.41) | GPR119PARP10PARP15PIK3CACNR2 | |
| SCHEMBL15539531 | 0.84 | GPR119 (0.41) | GPR119PARP10PARP15PIK3CACNR2 | |
| SCHEMBL16757768 | 0.84 | CNR2 (0.39) | GPR119PARP10PARP15PIK3CAMTOR | |
| SCHEMBL16757764 | 0.84 | CNR2 (0.39) | GPR119PARP10PARP15PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |